CAMEL DROMEDARY TUBERCULOSIS: A REVIEW

Volume 4, Issue 1, February 2021     |     PP. 1-22      |     PDF (308 K)    |     Pub. Date: June 8, 2021
DOI: 10.54647/ahvm23015    75 Downloads     101221 Views  

Author(s)

Dereje Teshome, Oromia Agricultural Research Institute; Yabello Pastoral and Dryland Agriculture Research Center, P.O. Box 85, Yabello, Ethiopia

Abstract
Camel is an important species uniquely adapted to arid and semi-arid environments and contributes significantly to the food security of the nomadic pastoral households. Tuberculosis caused by Maycobacterium bovis is the most common form of tuberculosis in camels. The two known Mycobacteria causing Tuberculosis in camels are Maycobacterium bovis and Maycobacterium tuberculosis. Tuberculosis in dromedaries has been documented since 1888 and its geographic distribution is with great variations between regions and countries. Transmission of the disease is mainly occurs by inhalation. Infected animal introduced in to a non-infected herd act as a source infection. In advanced cases the signs of the disease are; weakness, erratic appetite, and emaciation as well as low grade fluctuating fever. Enlarged superficial lymph nodes provide a useful sign for diagnosis. A presumptive diagnosis of tuberculosis in camel is often made based on history, clinical findings, tuberculin skin tests, post-mortem, bacteriological and molecular techniques. Treatment is not advised for animals. Control depends on the removal of infected animals and prevention of further introduction of infection into the herd. Conventional cost intensive test-and-slaughter schemes do not appear to be appropriate control measures for animal tuberculosis in developing countries. Tuberculosis, as a zoonosis from camel to human which is caused by principal agent; M. bovis plays an important role. In developing countries, the risk for contracting zoonotic tuberculosis is increased due to the higher infection rate in animals, absence of regular pasteurization of milk, cultural factors, poverty, malnutrition and a higher Human immune deficiency virus (HIV) infection rate. As a result, public awareness and appropriate control and prevention measures should be implemented to reduce the public health and economic burden of the disease. In general tuberculosis in animal as well as human is a challenging disease lack wide information on epidemiology, risk factors involved and role of M. bovis in human tuberculosis, so that significant further investigations are necessary for a better understanding of the disease; thus a better prevention and control of the infection in both animal and human.

Keywords
Camel dromedary, Review, Tuberculosis, Zoonosis.

Cite this paper
Dereje Teshome, CAMEL DROMEDARY TUBERCULOSIS: A REVIEW , SCIREA Journal of Animal Husbandry and Veterinary Medicine. Volume 4, Issue 1, February 2021 | PP. 1-22. 10.54647/ahvm23015

References

[ 1 ] Abbas B. and Omer H. (2006): "Review of infectious diseases of the camel". Animal Science. Data base, CABI Publishing.
[ 2 ] Abdurahman, O.S. and Bornstein, S. (1991): Diseases of camels (Camelus dromedarius) in Somalia and prospects for better health. Nomadic Peoples., 29: 104–112.
[ 3 ] Abebe, D. (2000): Pastoralism and Pastoral Production System. In: Proceeding of the Ethiopian Society of Animal Production (ESAP). August 2000. Addis Ababa, Ethiopia, pp. 1 – 5.
[ 4 ] Abera, D., Birhanu, T., Baker, T. (2014): Prevalence of Camel trypanosomosis at Selected Districts of Bale Zone, Southern Ethiopia. Sci. Technol. Arts Res. J.; 3(3): 103-106.
[ 5 ] Abubakar, U.B., Kudi, A.C., Abdulkadri, I.A. and Okaiyeto, S.O., 2014. Prevalence of tuberculosis in slaughter camels (Camelus dromedarius) at Kano abattoir, Nigeria based on lateral-flow technology. Journal of Camel Practice and Research., 21: 41–45.
[ 6 ] Alhebabi, A.M. and Alluwaimi, A.M. (2010): Paratuberculosis in Camel (Camelus dromedarius): The Diagnostic Efficiency of ELISA and PCR. Open Veterinary Science Journal., 4: 41-44.
[ 7 ] Ameni, G., Vordermeier, M.B., Firdessa, R.C., Aseffa, A.C., Hewinson, G.B., Gordon, S.V. and Berg, S. (2010):  Mycobacterium tuberculosis infection in grazing cattle in central Ethiopia. The Vet. J., 188:359-361.
[ 8 ] Ayele, WY., Neill, SO., Zinsstag, J., Weiss., MG., Pavlic, I. (2004): Bovine tuberculosis: an old disease but a new threat to Africa. Int. J. Tuberc. Lung Dis. 8: 924-937.
[ 9 ] Beyi, A.F., Gezahegne, K.Z., Mussa, A., Ameni, G. and Ali, M.S., 2014. Prevalence of bovine tuberculosis in dromedary camels and awareness of pastoralists about its zoonotic importance in Eastern Ethiopia. Journal of Veterinary Medicine and Animal Health., 6: 109–115.
[ 10 ] Bush, M., Montali, R., Philipps, L. and Holobaugh, P. (1990): Bovine tuberculosis in Bacterian camel herd: clinical, therapeutic and pathogenic finding. J. Zoo wildlife Med., 21: 71-179.
[ 11 ] Caleb, K., Abubakar, B.  and Awah, N. (2012): Prevalence of bovine tuberculosis in camels in Northern Nigeria. Journal of Camel Practice and Research., 19:81-86.
[ 12 ] Cosivi O., Meslin F.K., Daborn C.J., Grange J.M. (1995):The epidemiology of Mycobacterium bovis in infections in animals and humans, with particular reference to Africa. OIE Scientific and Technical Review, 14: 733–746.
[ 13 ] Cosivi, O.,Grange, J.M., Dabora, C.J., Ravighone, M.C., Fujikura, T., Cousins, D., Robinsen, R.A., Huchzermeyer, .A.K., deKantor, I. and Mesilin, F-X. (1998): Zoonotic tuberculosis due to Mycobacterium bovis in developing countrys.ImergingInfectios Diseases, 4:1-14.
[ 14 ] Cousins D.V. (2001): Mycobacterium bovis infection and control in domestic livestock. Rev Sci Tech. Apr;20(1):71-85.
[ 15 ] Dia, M.L. (2006): Parasites of the camel in Burkina Faso. Trop. Anim. Hlth., Prod., 38: 17-21.
[ 16 ] Domingo, M., Vidal, E. and Marco, A. (2014): Pathology of bovine tuberculosis, Research in Veterinary Science., 97: 20–29.
[ 17 ] Donchenko , A. S.; Donchenko, E. A.; Fatkeeva, E. A. and Kibsov. (1975): "Isolation of tuberculosis mycobacteria in camel milk, their survival in shubat and methods of decontamination of these products. Vest. Sel. Khoz, Nauk, Alma., 4:119-122.
[ 18 ] Dubie, T., Sisay, T., Zeru, F., Gebru, M., Negash, W. (2016): Preliminary assessesment on the epidemiology and Public health implication of camel tuberculosis in Pastoral area of Ethiopia. World Journal of Pharmaceutical Research, 5: 94-115.
[ 19 ] El Harrak, M., Faye, B. and Bengoumi, M. (2011): Main pathologies of camels, breeding of camels, constraints, benefits and perspectives. The OIE Regional Conference for the Middle East, Beirut, Lebanon, 3–6 October 2011.
[ 20 ] Elmossalami, E., Siam, M. E. and Sergany, M. (1971): Studies on tuberculosis-like lesions in slaughtered camels. Zentralblatt for Veterinary medicine., 18: 253–261.
[ 21 ] FAO (2013): Statistical year book.Food and Agriculture Organization of the United Nations, Rome, Italy, 2013.
[ 22 ] Grainanger, J. and Madden, D., 1993. The polymerase chain reaction: turning needles into haystacks. Biologist.; 5: 197-200.
[ 23 ] Grange, J.M. (2001): Mycobactrium bovis infection in human beings. Vet. Microbiol., 40:71-77.
[ 24 ] Gumi, B., Schelling, E., Berg, S., Firdessa, R., Erenso, G., Mekonnen, W., Hailu, E., Melese, E., Hussein, J., Aseffa, A., Zinsstag, J. (2012): Zoonotic transmission of tuberculosis between pastoralists and their Livestock in southeast Ethiopia. Econ. Health 9:139–149.
[ 25 ] Hirsh, A., Tsolaki, A., DeRiemer, K., Feldman, M., Small, P. (2004): Stable association between strains of Mycobacterium tuberculosis and their human host populations. Proceedings of the National Academy of Sciences of the United States of America., 101:4871–4876.
[ 26 ] Hirsh, D.C. and Zee, Y.C. (1999): Veterinary Microbacterium. 1st ed, USA: Blackwell Science. Pp. 163-164.
[ 27 ] Husein, A., Haftu, B., Hunde, A. and Tesfaye, A. (2013): Prevalence of camel (Camelus dromedaries) mastitis in Jijiga Town, Ethiopia. African Journal of Agricultural Research., 8: 3113-3120.
[ 28 ] Hussein, N. (2009); Study on Mycobacterium tuberculosis complex infection in livestock and humans in Amibara District of Afar Region. MSc Thesis, Addis Ababa University, Faculty of Veterinary Medicine, Debre-zeit, Ethiopia.
[ 29 ] Kamerbeek, J.L., Schous, A., Kolk, M., Argemed, D., Vansooligeten, S., Juijiper, A., Buschoten, H., Movizen, R., Goyal, M. and Van Embden, J. (1997): Simultaneous detection and differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology. J. clin.Microbiol., 35: 1907-1914.
[ 30 ] Kasaye, S., Molla, W. and Amini, G., 2013. Prevalence of camel tuberculosis at Akaki abattoir in Addis Ababa, Ethiopia. African Journal of Microbiology Research., 7: 2184–2189.
[ 31 ] Kidane, D., Olobo, JO., Habte, A., Negesse, Y., Aseffs, A., Abate, G., Yassin, MA., Betreda, K., Harboe, M. (2002): Identification of the causative organism of tuberculosis lymphadenitis in Ethiopia by PCR. J. Clin. Microbiol., 40: 4230-4234.
[ 32 ] Kinne, J., Johnson, B., Jahans, K.L., Smith, N.H., Ul-Haq, A. and Wernery, U. (2006): Camel tuberculosis a case report. Trop. Anim. Health Prod., 38, 207-213.
[ 33 ] Krauss, H. Schiefer, HG. Weber, A. Sclenczka, W. Appel, M. Graeventiz, AV. Enders, B. Zahner, H. Isenberg, DH. (2003): Zoonoses book: Infectious disease Transmissible from animals to Humans. 3rd ed. Washington DC: AM press, pp. 209-211.
[ 34 ] LoBue, PA., Betacourt, W., Peter, C., Moser, KS. (2003): Epidemiology of Mycobacterium bovis disease in San Diego County, 1994–2000. Int J Tuberc Lung Dis., 7:180–5.
[ 35 ] Mahamed, A Haji, A. Beriso, K Gebeyew, K. (2015): Small Holder Camel Milk Production Performance in Jigjiga District, Somali Regional State, Eastern Ethiopia. J Veterinar Sci Technol., 6: 267. doi:10.4172/2157-7579.1000267.
[ 36 ] Mamo, G. Kassaye, A. Sanni, M. Ameni, G. (2009): A cross sectional study of camel tuberculosis in Ethiopia. Bull. Anim. Health Prod. Afr., 57: 13-20.
[ 37 ] Mamo, G., Bayleyegn, G., Tessema, T. S., Legesse, M., Medhin, G., Bjune, G., Abebe, F. and Ameni, G. (2011): Pathology of camel tuberculosis and molecular characterization of its causative agents in pastoral regions of Ethiopia. Public Lib. Sci., One 6(1): e15862. doi:10.1371/journal.pone.0015862.
[ 38 ] Menzies, F. and Neill, S. (2000): Cattle to Cattle transmission of bovine tuberculosis. Vet. J, 160: 92-106.
[ 39 ] Michel, AL., Muller, B., Van Helden, PD. (2010): Mycobacterium bovis at the animal-human interface: a problem, or not? Vet Microbiol., 140:371–81.
[ 40 ] Ministry of Agriculture (MOA), (2013): Draft document on the establishment of Disease-free zones, Ministry of griculture, Ethiopia, pp: 23.
[ 41 ] Müller, B., Dürr, S., Alonso, S., Hattendorf, J., Laisse, CJM., Parsons, SDC., et al. ( 2013): Zoonotic Mycobacterium bovis–induced tuberculosis in humans. Emerg Infect Dis [Internet]. Jun [date cited]. http://dx.doi.org/10.3201/eid1906.120543.
[ 42 ] Munyeme, M., Muma, J., Skjerve, E., Nambota, A. and Phiri, I.(2008): Risk Factors Associated with Bovine Tuberculosis in Traditional Cattle of the Livestock/Wildlife Interface Areas in the Kafue Basin of Zambia. Prev Vet Med, 85: 317–328.
[ 43 ] Mustafa I.E. (1987): Bacterial diseases of dromedaries and bactrian camels. Rev. sci. tech. Off. int. Epiz., 6 (2), 391–405.
[ 44 ] Narnaware, SD., Dahiya, SS., Tuteja, FC., Nagarajan, G., Nath, K., Patil, NV. (2015): Pathology and diagnosis of Mycobacterium bovis in naturally infected dromedary camels (Camelus dromedarius) in India. Trop Anim Health Prod., 47(8):1633-6. doi: 10.1007/s11250-015-0905-5.
[ 45 ] Ndukum, A., CalebKudi, A., Bradley, G., Ane- Anyangwe, I.N., Fon-Tebug, S. and Tchoumboue, J. (2010): Prevalence of bovine tuberculosis in abattoirs of the littoral and western highland regions of Cameroon: a cause for public health concern, SAGE-Hindawi Access to Research. Veterinary Medicine International Article ID 495015, doi: 10.4061/2010/495015.
[ 46 ] Office of international des epizootics (OIE) (2009): Bovine Tuberculosis. World organization for animal health manual of diagnostic tests and vaccines for terrestrial animals (mammals, birds and bees). 6th Edition, Paris, Pp. 1–16.
[ 47 ] Office of international des epizootics (OIE). (2004): Bovine tuberculosis; In manual of diagnostic tests and vaccines for terrestrial animals (mammals, birds and bees). 5th ed. World organization for animal health, Pp. 451-463. 
[ 48 ] Osrowski, S., Bedin, E., Lenain, M. and Auzinada, H. (1998): Ten years of Arabian achievements and regional perspective. Oryx, 32: 209.
[ 49 ] Ozyigit, M., Senturk, S. and Akkoc, A. (2007): Suspected Congenital Generalized Tuberculosis in a Newborn Calf. Vet Rec., 160: 307–308.
[ 50 ] Phillips, C., Foster, C., Morris, P and Teverson, R. (2003): The Transmission of Mycobacterium bovis Infection in Cattle. Res Vet Sci., 74: 1–15.
[ 51 ] Pierle, C., Lecossier, D., Boussovgant, Y., Bocart, D., Joly, V. and Hance, A.J. (1991): Use of amplification protocol improves sensitivity of detection of mycobacterium bovis in clinical sample by amplification of DNA. J. Clin. Microbiol., 29:712-717.
[ 52 ] Quinn, J.P., Carter, M., Donnelly, C.J.W. and Leonard, C.F. (2002): Veterinary Microbiology and Microbial Diseases. 1st ed, Great Britian: Blackwell Science. Pp. 113-118.
[ 53 ] Quinn, JP, Markey, BK (2003): Concise review of veterinary microbiology. 2nd Ed. USA: Blackwell publishing, pp. 34-35.
[ 54 ] Radostits, O., Gay, C., Blood, D. and Hinchclif, K. (2007): Veterinary medicine. A text book of the disease of cattle, sheep, pigs, goats and horses. 10thed. London, Saunder Elsevier. Pp.471-500.
[ 55 ] Radostits, O.M., Gay, C.C., Blood, D.C. and Hinchcliff, K.W. (2000): Deborah Russell (ed). Atext book of the diseases of Cattle, Sheep, Goat and Horses, 9thed. Harcout Publishers Ltd, London. Pp.909-919.
[ 56 ] Samuel, K. A. (2010): Molecular characterization of mycobacterial species isolated from tuberculous lesions seen in bovine carcasses at postmortem: a case study of three abattoirs in the Accra Region of Ghana. A thesis Master of Science, Ghana.
[ 57 ] Schillinger, D. (1987): Camel (Camelus dromedarius). Seminarson derdruck Vet. Labhard Verlag Konstanz., 9;50–53.
[ 58 ] Seifert, H.S.H. (1992): Tropentierhygiene, (Gustav Fischer Verlag, Jena), p.285–289.
[ 59 ] Shitaye, JE., Tsegaye, W., Pavlik, I. (2007): Bovine tuberculosis infection in animal and human populations in Ethiopia: A review. Vet. Med., 52(8): 317-332.
[ 60 ] Sisay, F. and Awoke, K. (2015): Review on Production, Quality and Use of Camel Milk in Ethiopia. J Fisheries Livest Prod., 3: 145.
[ 61 ] Smith, B.P. (2009): Large animal internal medicine .4th ed. Mosby, inc, an affiliate of Elsevier inc. p.873-897.
[ 62 ] Srivastava, K., Chaouhan, D.S., Gupta, P., Singh, H.B., Sharma, V.D., Yadar, F., Sreekumaran, V.S., Thakari, S.S., Dharamadhee, J.S., Nigam, P., Prasad, H.K. and Katoch, V.M. (2008): Isolation of Mycobacterium bovis and Mycobacterium tuberculosis from catlle of some farming in North India: possible relevance in human health. Indian J. Med. Reser., 1: 10-12.
[ 63 ] Tessema, B., Beer, J., Emmrich, F., Sack, U. and Rodloff, A.C. (2011): Rate of Recovery of Mycobacterium tuberculosis from Frozen Acid-Fast-Bacillus Smear-Positive Sputum Samples Subjected to Long-Term Storage in Northwest Ethiopia. JCLIMICR., 49: 2557–2561.
[ 64 ] Thoen C.O., LoBue P.A. & de Kantor I. (2006): The importance of Mycobacterium bovis as a zoonosis. Vet. Microbiol., 112 (2–4), 339–345.
[ 65 ] Thoen, C.O., Lobue, P.A., Enarson, D.A., Kaneene, J.B. and de Kantor, I.N. (2009): Tuberculosis: a re-emerging disease in animals and humans. Veterinari Italiana., 45: 135-181.
[ 66 ] Thoen, O.C. and Steele, J.H. (1995): Mycobacterium bovis infection and transmission in humans and animals. Iowa state University press. Ame ., 24: 15-165.
[ 67 ] Wards, B.J., Collins, D.M. and Delsile, G.W. (1995): Detection of Mycobacterium bovisin tissues by polymerase reaction. Vet. Microbio. p. 227-240.
[ 68 ] Waters, W.R., Palmer, M.V., Thacker, T.C., Bannantine, J.P., Vordermeier, H.M., Hewinson, R.G., Greenwald R., Esfandiari J., McNair J., Pollock J.M., Andersen P. & Lyashchenko, K.P. (2006): Early antibody responses to experimental Mycobacterium bovis infection of cattle. Clin. vaccine Immunol., 13 (6), 648–654.
[ 69 ] Wernery, U and Kaaden, OR. (2002): Infectious diseases of camelids. Blackwell Science, Berlin, pp. 23-373.
[ 70 ] Wernery, U. and Kinne, J. (2012): Tuberculosis in camelids: a review. Rev.sci. tech. Off. int. Epiz., 31 (3): 899-906
[ 71 ] Wernery, U., Kinne, J., Jahans, K.L., Vordermeier, H.M., Esfandiari, J., Greenwald, R., Johnson, B., Ul-Haq, A. & Lyashchenko K.P. (2007): Tuberculosis outbreak in a dromedary racing herd and rapid serological detection of infected camels. Vet. Microbiol., 122 (1–2): 108–115.
[ 72 ] Windsor, R. (1999): Bovine tuberculosis in alpacas and llamas. Proceed. Bri. Vet Camelid Soc. Penrith, UK, Pp 32-34.
[ 73 ] World Health Organization. (2008): Profiles of High-Burden Countries, Geneva: Switzerland, World Health Organization.
[ 74 ] World Health Organization. (2011): Global tuberculosis control. WHO Report. Geneva: The Organization.
[ 75 ] Zerom, K., Tesfaye T., Mamo, G., Bayu, Y. and Ameni, G. (2012): Tuberculosis in dromedaries in Eastern Ethiopia: Abattoir-based prevalence and molecular typing of its causative agents. Small Rumin. Res., 109: 188-192.
[ 76 ] Zubair, R., Khan, A.M.Z. and Sabri, M.A. (2004): Pathology of Camel Lungs. J. of Camel Scien., 1:103-106.