Edible bird’s nest: extraction and pharmacological

Volume 1, Issue 1, October 2016     |     PP. 1-20      |     PDF (563 K)    |     Pub. Date: November 17, 2016
DOI:    448 Downloads     7728 Views  

Author(s)

Qianwen Li, College of Pharmacy, JiNan University, P. R. China
Yueling Yuan, College of Pharmacy, JiNan University, P. R. China
Ronghua Zhang, College of Pharmacy, JiNan University, P. R. China
Li Yang, College of Pharmacy, JiNan University, P. R. China
Li Han, Hospital of JiNan University, P. R. China
Tiange Cai, College of Life Sciences, LiaoNing University, P. R. China
Yu Cai, College of Pharmacy, JiNan University, P. R. Chinal; Cancer Research Institute of JiNan University, P. R. China

Abstract
Abstract:Edible bird’s nests (EBNs) are nests built with saliva and feather by swiftlets (Apodidiae) in the breeding season. It is one of the precious Chinese traditional medicines that are reported to have high economic and medicinal values. Biological activity and pharmacological effects of EBN has attracted more attention with the consumption of EBN increasing in recent years. we summarized and analyzed the extraction and pharmacological effects of the edible bird's nest in recent 5 years. To provide the basis for further study on mechanism of pharmacological effects of edible bird's nest. The edible bird's nest contains protein, amino acids, carbohydrates and minerals. The different extraction in the edible bird's nest is not the same. EBN not only can be used to anti-aging, antioxidant, anti-virus, anti-inflammatory, immune promoting, regulation of intestinal flora. but also can be used to prevent osteoarthritis, improve bone strength in postmenopausal women, improve corneal injury, improve cell apoptosis, prevent high fat diet induced insulin resistance. This article reviewedthe extraction and pharmacological effects of the edible bird's nest. At last, this article prospected research directions in order to provide a basis for further study on EBN.

Keywords
edible bird's nest, extraction , pharmacological effects.

Cite this paper
Qianwen Li, Yueling Yuan, Ronghua Zhang, Li Yang, Li Han, Tiange Cai, Yu Cai, Edible bird’s nest: extraction and pharmacological , SCIREA Journal of Medicine. Volume 1, Issue 1, October 2016 | PP. 1-20.

References

[ 1 ] Chen JX, Wong SF, Lim PK, Mak JW. Culture and molecular identification of fungal contaminants in edible bird nests. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2015;32(12):2138-47.
[ 2 ] Chen Q, Guo Y. Influenza viral hemagglutinin peptide inhibits influenza viral entry by shielding the host receptor. ACS Infect Dis 2016;2(3):187-93.
[ 3 ] Chua KH, Lee TH, Nagandran K, Yahaya NHM, Lee CT, Tjih ET, Aziz RA. Edible bird's nest extract as a chondro-protective agent for human chondrocytes isolated from osteoarthritic knee: in vitro study.BMC Complement Altern Med 2013;13(19):1-9.
[ 4 ] Chua YG, Chan SH, Bloodworth BC, Lee SF, and Leong LP. Identification of edible Bird's nest with amino acid and monosaccharide analysis. J Agric Food Chem (2015); 63(1):279-89.
[ 5 ] Goh DL, Chew FT, Chua KY, Chay OM, and Lee BW. Edible "bird's nest"-induced anaphylaxis: An under-recognized entity?. J Pediatr (2000); 37(2):277-9.
[ 6 ] Guo CT, Takahashi T, Bukawa W, Takahashi N, Yagi H, Kato K, Hidari KI, Miyamoto D, Suzuki T, and Suzuki Y. Edible bird's nest extract inhibits influenza virus infection. Antiviral Res (2006);70(3): 140-6.
[ 7 ] Haghani A, Mehrbod P, Safi N, Aminuddin NA, Bahadoran A, Omar AR, and Ideris A. In vitro and in vivo mechanism of immunomodulatory and antiviral activity of Edible Bird's Nest (EBN) against influenza A virus (IAV) infection. J Ethnopharmacol (2016);185: 327-40.
[ 8 ] Hou Z, Imam MU, Ismail M, Azmi NH, Ismail N, Ideris A, and Mahmud R. Lactoferrin and ovotransferrin contribute toward antioxidative effects of Edible Bird's Nest against hydrogen peroxide-induced oxidative stress in human SH-SY5Y cells. Biosci Biotechnol Biochem (2015);79(10): 1570-8.
[ 9 ] Hou Z, Imam MU, Ismail M, Ooi DJ, Ideris A, and Mahmud R. Nutrigenomic effects of edible bird's nest on insulin signaling in ovariectomized rats. Drug Des Devel Ther (2015);9: 4115-25.
[ 10 ] Liu L, Li XL, Gao JP, Kong YJ, Wang ML, Zhang GF, and Su ZG. Peptides analysis in digested edible bird's nest by HPLC-MS. Zhongguo Zhong Yao Za Zhi (2013);38(5): 714-9.
[ 11 ] Liu X, Lai X, Zhang S, Huang X, Lan Q, Li Y, Li B. Proteomic profile of edible bird's nest proteins. J Agric Food Chem (2012);60(51): 12477-81.
[ 12 ] Matsukawa N, Matsumoto M, Bukawa W, Chiji H, Nakayama K, Hara H, and Tsukahara T. Improvement of bone strength and dermal thickness due to dietary edible bird's nest extract in ovariectomized rats. Biosci Biotechnol Biochem (2011);75(3): 590-2.
[ 13 ] Nakagawa H, Hama Y, Sumi T, Li SC, Maskos K, Kalayanamitra K, Mizumoto S, Sugahara K, and Li YT. Occurrence of a nonsulfated chondroitin proteoglycan in the dried saliva of Collocalia swiftlets (edible bird's-nest). Glycobiology (2007);17(2): 157-64.
[ 14 ] Norhayati MK, Azman Jr O, and Nazaimoon W Wan. Preliminary Study of the Nutritional Content of Malaysian Edible Bird's Nest. Malays J Nutr (2010);16(3): 389-96.
[ 15 ] Roh KB, Lee J, Kim YS, Park J, Kim JH, Lee J, and Park D. Mechanisms of Edible Bird's Nest Extract-Induced Proliferation of Human Adipose-Derived Stem Cells. Evid Based Complement Alternat Med 2012 (2012): 797520.
[ 16 ] Ryu MJ, Kang KA, Piao MJ, Kim KC, Zheng J, Yao CW, Cha JW. 7,8-Dihydroxyflavone protects human keratinocytes against oxidative stress-induced cell damage via the ERK and PI3K/Akt-mediated Nrf2/HO-1 signaling pathways. Int J Mol Med (2014);33(4): 964-70.
[ 17 ] Tukiran NA, Ismail A, Mustafa S, and Hamid M. Enzyme immunoassay for the detection of porcine gelatine in edible bird's nests. Food Addit Contam Part A Chem Anal Control Expo Risk Assess (2015);32(7): 1023-8.
[ 18 ] Vimala B, Hussain H, and Nazaimoon WMW. Effects of edible bird's nest on tumour necrosis factor-alpha secretion, nitric oxide production and cell viability of lipopolysaccharide-stimulated RAW 264.7 macrophages. Food and Agricultural Immunology (2012);23(4): 303-14.
[ 19 ] Wang LL, Chen N, Zhang WW, Wu GH, and Lai XP. Study on a collagenase protocol to extract DNA from remnant feathers in edible bird's nest. Zhong Yao Cai (2013);36(8):1224-6.
[ 20 ] Wong RS. Edible bird's nest: food or medicine? Chin J Integr Med (2013);19(9):643-9.
[ 21 ] Xian XM, Hou Y, Lin JR, Huang S, Lai XP, and Chen JN. Study on degradation of protein of the edible birds' nest (Aerodramus) in vitro. Zhong Yao Cai (2010);33(11): 1760-3.
[ 22 ] Yagi H, Yasukawa N, Yu SY, Guo CT, Takahashi N, Takahashi T, Bukawa W.The expression of sialylated high-antennary N-glycans in edible bird's nest.Carbohydr Res (2008);343(8):1373-7.
[ 23 ] Yang M, Cheung SH, Li SC, and Cheung HY. Establishment of a holistic and scientific protocol for the authentication and quality assurance of edible bird's nest. Food Chem (2014);151: 271-8.
[ 24 ] Yew MY, Koh RY, Chye SM, Othman I, and Ng KY. Edible bird's nest ameliorates oxidative stress-induced apoptosis in SH-SY5Y human neuroblastoma cells. BMC Complement Altern Med (2014);14: 391.
[ 25 ] Yida Z, Imam MU, and Ismail M.In vitro bioaccessibility and antioxidant properties of edible bird's nest following simulated human gastro-intestinal digestion. BMC Complement Altern Med (2014);14: 468.
[ 26 ] Yida Z, Imam MU, Ismail M, Hou Z, Abdullah MA, Ideris A, and Ismail N. Edible Bird's Nest attenuates high fat diet-induced oxidative stress and inflammation via regulation of hepatic antioxidant and inflammatory genes. BMC Complement Altern Med (2015);15: 310.
[ 27 ] Yida Z, Imam MU, Ismail M, Ismail N, and Hou Z. Edible bird's nest attenuates procoagulation effects of high-fat diet in rats. Drug Des Devel Ther (2015);9: 3951-9.
[ 28 ] Yida Z, Imam MU, Ismail M, Ooi DJ, Sarega N, Azmi NH, Ismail N, Chan KW, Hou Z, and Yusuf NB. Edible Bird's Nest Prevents High Fat Diet-Induced Insulin Resistance in Rats. J Diabetes Res (2015): 76053-5.
[ 29 ] Yu-Qin Y, Liang X, Hua W, Hui-Xing Z, Xin-Fang Z, and Bu-Sen L. Determination of edible bird's nest and its products by gas chromatography. J Chromatogr Sci (2000);38(1): 27-32.
[ 30 ] Zainal Abidin F, Hui CK, Luan NS, Mohd Ramli ES, Hun LT, and Abd Ghafar N. Effects of edible bird's nest (EBN) on cultured rabbit corneal keratocytes. BMC Complement Altern Med (2011);11: 94.
[ 31 ] Zhang S, Lai X, Liu X, Li Y, Li B, Huang X, Zhang Q, Chen W, Lin L, and Yang G.Competitive enzyme-linked immunoassay for sialoglycoprotein of edible bird's nest in food and cosmetics. J Agric Food Chem (2012):60(14): 3580-5.
[ 32 ] Zhao B, Deng XM, Wang LL, Li G, and Lai XP. Characterization of Aldoses in Edible Bird's Nest from Southeast Asia by Gas Chromatography. Zhong Yao Cai (2015);38(1): 25-8.
[ 33 ] Zhao R, Li G, Kong XJ, Huang XY, Li W, Zeng YY, and Lai XP. The improvement effects of edible bird's nest on proliferation and activation of B lymphocyte and its antagonistic effects on immunosuppression induced by cyclophosphamide. Drug Des Devel Ther (2016); 10:371-81.
[ 34 ] Zheng W, Wang Q, Lu X, Shi Q, Zou J, Tao Y, and Wang P. Protective Effects of Dracocephalum heterophyllum in ConA-Induced Acute Hepatitis. Mediators Inflamm 2016 (2016): 268432-1.
[ 35 ] Zhiping H, Imam MU, Ismail M, Ismail N, Yida Z, Ideris A, Sarega N, and Mahmud R. Effects of edible bird's nest on hippocampal and cortical neurodegeneration in ovariectomized rats. Food Funct (2015);6(5): 1701-11.